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Respiratory Congestion
Mucociliary System
Treatment Options
Societal and Economic Impact
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Antibiotic Resistance

  • Reducing use of antibiotics when they are not needed is the best way to counter the threat of antibiotic resistance and preserve effective antibiotics for the future2
    • - In a landmark study conducted in Finland, a 40% reduction in macrolide use was associated with a 48% decrease in prevalence of erythromycin resistance among group A streptococcal isolates over 5 years3

The role of antibiotics in respiratory care

  • Acute respiratory infection (ARI) symptoms are the most frequent reason for seeking medical attention in the United States4
  • 75% of antibiotic prescriptions each year are associated with ARIs3
    • - Yet 98% of ARIs, including the common cold, are not complicated by bacterial infections that require antibiotics5

Satisfying patient expectations

  • Every physician visit is an opportunity to reinforce appropriate antibiotic use and provide counseling to satisfy expectations
What patients with URI expect from their physician visit6*
Adult Patient Illness Duration
What Is Wanted 0-2 Days 3-5 Days >5 Days
Reassurance 77.8 72.0 68.5
Reduced worry about complications 84.7 64.1 70.6
Antibiotics 44.4 43.0 60.4
Cough medication 20.8 21.5 19.6
Throat culture 27.8 29.0 15.2
Relief from cold 76.4 81.5 92.4
Resume activities 68.1 72.0 68.5
Return to work 40.9 34.4 31.8

*Shown with permission from: Solberg LI, Braun BL, Fowles JB, Kind EA, Anderson RS, Healey ML. Care-seeking behavior for upper respiratory infections. J Fam Pract. 2000;49(10):915-920.

No patients wanted a chest x-ray and only 15 (3%) wanted a sinus x-ray, with no difference by duration of illness at visit.

  • Only 43% of these patients actively sought an antibiotic within 3 to 5 days of illness6

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Centers for Disease Control and Prevention

National Institute of Allergy and Infectious Diseases

US Food and Drug Administration

References: 1. LaForce C, Gentile DA, Skoner DP. A randomized, double-blind, parallel-group, multicenter, placebo-controlled study of the safety and efficacy of extended-release guaifenesin/pseudoephedrine hydrochloride for symptom relief as an adjunctive therapy to antibiotic treatment of acute respiratory infections. Postgrad Med. 2008;120(2):1-7. 2. Centers for Disease Control and Prevention Web site. Get smart: know when antibiotics work. Accessed January 6, 2009. 3. Seppälä H, Klaukka T, Vuopio-Varkila J, et al. The effect of changes in the consumption of macrolide antibiotics on erythromycin resistance in group A streptococci in Finland. N Engl J Med. 1997;337(7):441-446. 4. Gonzales R, Bartlett JG, Besser RE, Cooper RJ. Principles of appropriate antibiotic use for treatment of acute respiratory tract infections in adults: background, specific aims, and methods. Ann Intern Med. 2001;134:479-486. 5. Centers for Disease Control and Prevention Web site. Nonspecific upper respiratory tract infection. Accessed January 6, 2009. 6. Solberg LI, Braun BL, Fowles JB, Kind EA, Anderson RS, Healey ML. Care-seeking behavior for upper respiratory infections. J Fam Pract. 2000;49(10):915-920.

mucinex d helps patients feel better

Review the results of adding MUCINEX D as an adjunct to an antibiotic in the treatment of ARI

For access to the study published in Postgraduate Medicine, click here.

MUCINEX in. mucus out.