- Reducing use of antibiotics when they are not needed is the best way to counter the threat of antibiotic resistance and preserve effective antibiotics for the future2
- - In a landmark study conducted in Finland, a 40% reduction in macrolide use was associated with a 48% decrease in prevalence of erythromycin resistance among group A streptococcal isolates over 5 years3
The role of antibiotics in respiratory care
- Acute respiratory infection (ARI) symptoms are the most frequent reason for seeking medical attention in the United States4
- 75% of antibiotic prescriptions each year are associated with ARIs3
- - Yet 98% of ARIs, including the common cold, are not complicated by bacterial infections that require antibiotics5
Satisfying patient expectations
- Every physician visit is an opportunity to reinforce appropriate antibiotic use and provide counseling to satisfy expectations
|Adult Patient Illness Duration|
|What Is Wanted||0-2 Days||3-5 Days||>5 Days|
|Reduced worry about complications||84.7||64.1||70.6|
|Relief from cold||76.4||81.5||92.4|
|Return to work||40.9||34.4||31.8|
*Shown with permission from: Solberg LI, Braun BL, Fowles JB, Kind EA, Anderson RS, Healey ML. Care-seeking behavior for upper respiratory infections. J Fam Pract. 2000;49(10):915-920.
†No patients wanted a chest x-ray and only 15 (3%) wanted a sinus x-ray, with no difference by duration of illness at visit.
- Only 43% of these patients actively sought an antibiotic within 3 to 5 days of illness6
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References: 1. LaForce C, Gentile DA, Skoner DP. A randomized, double-blind, parallel-group, multicenter, placebo-controlled study of the safety and efficacy of extended-release guaifenesin/pseudoephedrine hydrochloride for symptom relief as an adjunctive therapy to antibiotic treatment of acute respiratory infections. Postgrad Med. 2008;120(2):1-7. 2. Centers for Disease Control and Prevention Web site. Get smart: know when antibiotics work. http://www.cdc.gov/drugresistance/community/know-and-do.htm. Accessed January 6, 2009. 3. Seppälä H, Klaukka T, Vuopio-Varkila J, et al. The effect of changes in the consumption of macrolide antibiotics on erythromycin resistance in group A streptococci in Finland. N Engl J Med. 1997;337(7):441-446. 4. Gonzales R, Bartlett JG, Besser RE, Cooper RJ. Principles of appropriate antibiotic use for treatment of acute respiratory tract infections in adults: background, specific aims, and methods. Ann Intern Med. 2001;134:479-486. 5. Centers for Disease Control and Prevention Web site. Nonspecific upper respiratory tract infection. http://www.cdc.gov/drugresistance/community/hcp-info-sheets/adult-nurti.htm. Accessed January 6, 2009. 6. Solberg LI, Braun BL, Fowles JB, Kind EA, Anderson RS, Healey ML. Care-seeking behavior for upper respiratory infections. J Fam Pract. 2000;49(10):915-920.
Review the results of adding MUCINEX D as an adjunct to an antibiotic in the treatment of ARI
For access to the study published in Postgraduate Medicine, click here.